Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety.
Clicks: 314
ID: 104488
2019
Reaction of 1-adamantyl carbohydrazide () with various substituted benzaldehydes and acetophenones yielded the corresponding hydrazide-hydrazones with a 1-adamantane carbonyl moiety. The new synthesized compounds were tested for activities against some Gram-negative and Gram-positive bacteria, and the fungus . Compounds , , , and displayed potential antibacterial activity against tested Gram-positive bacteria and , while compounds and possessed cytotoxicity against tested human cancer cell lines.
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| Authors | Pham, Van Hien;Phan, Thi Phuong Dung;Phan, Dinh Chau;Vu, Binh Duong; |
| Journal | Molecules (Basel, Switzerland) |
| Year | 2019 |
| DOI | E4000 |
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