Delivery in pregnant women infected with SARS-CoV-2: A fast review.

Clicks: 264
ID: 106523
2020
Few case reports and clinical series exist on pregnant women infected with SARS-CoV-2 who delivered.To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SARS-CoV-2.Combination of the following key words: COVID-19, SARS-CoV-2, and pregnancy in Embase and PubMed databases.Papers reporting cases of women infected with SARS-CoV-2 who delivered.The following was extracted: author; country; number of women; study design; gestational age at delivery; selected clinical maternal data; mode of delivery; selected neonatal outcomes.In the 13 studies included, vaginal delivery was reported in 6 cases (9.4%; 95% CI, 3.5-19.3). Indication for cesarean delivery was worsening of maternal conditions in 31 cases (48.4%; 95% CI, 35.8-61.3). Two newborns testing positive for SARS-CoV-2 by real-time RT-PCR assay were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated but the RT-PCR test was negative.The rate of vertical or peripartum transmission of SARS-CoV-2 is low, if any, for cesarean delivery; no data are available for vaginal delivery. Low frequency of spontaneous preterm birth and general favorable immediate neonatal outcome are reassuring.
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Authors Parazzini, Fabio;Bortolus, Renata;Mauri, Paola Agnese;Favilli, Alessandro;Gerli, Sandro;Ferrazzi, Enrico;
Journal International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Year 2020
DOI 10.1002/ijgo.13166
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