Once-daily valacyclovir to reduce the risk of transmission of genital herpes

Clicks: 442
ID: 114793
2004
Once-daily suppressive therapy with valacyclovir significantly reduces the risk of transmission of genital herpes among heterosexual, HSV-2-discordant couples.
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Authors Corey L;Wald A;Patel R;Sacks SL;Tyring SK;Warren T;Douglas JM;Paavonen J;Morrow RA;Beutner KR;Stratchounsky LS;Mertz G;Keene ON;Watson HA;Tait D;Vargas-Cortes M; ;;
Journal The New England journal of medicine
Year 2004
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/14702423
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male adolescent aged middle aged Drug Administration Schedule P.H.S. Clinical Trial Randomized Controlled Trial Multicenter Study herpes genitalis / transmission infectious / prevention & control* disease transmission herpesvirus 2 anna wald lawrence corey human* / isolation & purification pmid:14702423 doi:10.1056/nejmoa035144 valacyclovir hsv transmission study group acyclovir / administration & dosage* acyclovir / analogs & derivatives* antiviral agents / administration & dosage* herpes genitalis / drug therapy* human* / physiology safe sex valacyclovir valine / administration & dosage* valine / analogs & derivatives* virus activation / drug effects

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