Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Clicks: 307
ID: 116241
2018
Hippo signaling has been recognized as a key tumor suppressor pathway. Here, we perform a comprehensive molecular characterization of 19 Hippo core genes in 9,125 tumor samples across 33 cancer types using multidimensional "omic" data from The Cancer Genome Atlas. We identify somatic drivers among H …
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y2018cellcomprehensive
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| Authors | Wang Y;Xu X;Maglic D;Dill MT;Mojumdar K;Ng PK;Jeong KJ;Tsang YH;Moreno D;Bhavana VH;Peng X;Ge Z;Chen H;Li J;Chen Z;Zhang H;Han L;Du D;Creighton CJ;Mills GB; ;Camargo F;Liang H;; |
| Journal | Cell reports |
| Year | 2018 |
| DOI | DOI not found |
| URL | |
| Keywords |
Tumor
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
gene expression regulation
humans
pubmed abstract
nih
national institutes of health
national library of medicine
models
prognosis
research support
non-u.s. gov't
N.I.H.
Extramural
cell line
han liang
Base Sequence
micrornas / genetics
biological
neoplastic
mutation / genetics
pmid:30380420
pmc6326181
doi:10.1016/j.celrep.2018.10.001
yumeng wang
xiaoyan xu
micrornas / metabolism
neoplasms / metabolism*
protein-serine-threonine kinases / metabolism*
signal transduction* / genetics
|
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