Primary pneumonic plague in the African Green monkey as a model for treatment efficacy evaluation
Clicks: 297
ID: 119843
2011
Inhaled Y. pestis in the AGM results in a rapidly progressive and uniformly fatal disease with fever and multifocal pneumonia, serving as a rigorous test model for antibiotic efficacy studies.
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rc2011journalprimary
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Authors | Layton RC;Brasel T;Gigliotti A;Barr E;Storch S;Myers L;Hobbs C;Koster F;; |
Journal | journal of medical primatology |
Year | 2011 |
DOI | DOI not found |
URL | |
Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
female
male
N.I.H.
Extramural
Disease Models
animal*
plague / diagnosis
heart rate
electrocardiography
inhalation
lung / pathology
fever
lung / microbiology
radiography
bacteremia
plague / physiopathology
l-lactate dehydrogenase / blood
frederick koster
pmid:20722770
pmc2991483
doi:10.1111/j.1600-0684.2010.00443.x
r colby layton
trevor brasel
chlorocebus aethiops*
monkey diseases / microbiology*
plague / veterinary*
thoracic / veterinary
respiratory rate
telemetry
yersinia pestis* / isolation & purification
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