synthesis of 3-aryl-4-({2-[4-(6-substituted-coumarin-3-yl)-1,3-thiazol-2-yl]hydrazinylidene}methyl/ethyl)-sydnones using silica sulfuric acid and their antidiabetic, dna cleavage activity
Clicks: 190
ID: 135787
2016
A novel one-pot synthesis of sydnones appended to coumarins (4a–r) via thiazole in presence of silica sulfuric acid as a heterogeneous catalyst is discussed. The use of low cost and reusable silica sulfuric acid as catalyst makes this process feasible and convenient. Further, the title compounds were screened for their α-amylase inhibition (antidiabetic) as well as DNA cleavage activities.
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tegginamath2016arabiansynthesis
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| Authors | ;Gireesh Tegginamath;Ravindra R. Kamble;Pramod P. Kattimani;Sheetal B. Margankop |
| Journal | Behavioural brain research |
| Year | 2016 |
| DOI | 10.1016/j.arabjc.2011.04.006 |
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