trip to immunity: resistant cytomegalovirus infection in a lung transplant recipient

Clicks: 167
ID: 160834
2014
We report the case of a young female lung transplant recipient with difficult-to-treat cytomegalovirus (CMV) disease. While treatment with intravenous (IV) ganciclovir failed due to antiviral drug resistance, a trial with foscarnet resulted in severe side effects. In addition, the patient received IV CMV-specific immune globulins as adjunctive therapy and leflunomide as experimental therapy. In this context, CMV-specific immune monitoring was performed and was successfully implemented in management decisions. The patient was screened for acquisition of an adaptive immune response, and antiviral prophylaxis and therapy was tailored according to results. This report highlights the impact of CMV-specific immune monitoring on individualized therapy for appropriate prophylaxis and management of CMV infection and diseases.
Reference Key
kneidinger2014internationaltrip Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Nikolaus Kneidinger;Clemens Giessen;Werner von Wulffen;Katrin Milger;René Schramm;Gundula Jäger;Hans Nitschko;Hannah Striebinger;Jürgen Behr;Claus Neurohr
Journal israel journal of chemistry
Year 2014
DOI 10.1016/j.ijid.2014.06.009
URL
Keywords

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

No comments yet. Be the first to comment on this article.