current understanding of the trypanosoma cruzi-cardiomyocyte interaction
Clicks: 214
ID: 162201
2012
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits multiple strategies to ensure its establishment and persistence in the host. Although this parasite has the ability to infect different organs, heart impairment is the most frequent clinical manifestation of the disease. Advances in knowledge of T. cruzi-cardiomyocyte interactions have contributed to a better understanding of the biological events involved in the pathogenesis of Chagas disease. This brief review focuses on the current understanding of molecules involved in T. cruzi-cardiomyocyte recognition, the mechanism of invasion, and on the effect of intracellular development of T. cruzi on the structural organization and molecular response of the target cell.
| Reference Key |
calvet2012frontierscurrent
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Claudia Magalhães Calvet;Tatiana Galvão Melo;Luciana Ribeiro Garzoni;Francisco Odencio Rodrigues Oliveira-Jr;Dayse Teixeira Silva Neto;Maria de Nazareth Silveira Leal Meirelles;Mirian Claudia De Souza Pereira |
| Journal | sudebno-meditsinskaia ekspertiza |
| Year | 2012 |
| DOI | 10.3389/fimmu.2012.00327 |
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.