Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria.

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ID: 2057
2018
Eight undescribed triterpenoid saponins, scabiostellatosides A-H, together with three known compounds were isolated from the whole plant of Scabiosa stellata L. Their structures were established by spectroscopic analyses (1D, 2D-NMR and HRESIMS) and chemical methods. Scabiostellatosides A-H were evaluated for their cytotoxicity against human fibrosarcoma cell line (HT1080). Scabiostellatoside F, a heptasaccharide derivative of oleanolic acid, exhibited moderate cytotoxicity against HT1080 cell line with IC value of 12.0 μM.
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Authors Lehbili, Meryem;Alabdul Magid, Abdulmagid;Kabouche, Ahmed;Voutquenne-Nazabadioko, Laurence;Morjani, Hamid;Harakat, Dominique;Kabouche, Zahia;
Journal Phytochemistry
Year 2018
DOI S0031-9422(18)30061-X
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