sailing to and docking at the immune synapse: role of tubulin dynamics and molecular motors
Clicks: 164
ID: 206847
2018
The different cytoskeleton systems and their connecting molecular motors move vesicles and intracellular organelles to shape cells. Polarized cells with specialized functions display an exquisite spatio-temporal regulation of both cytoskeletal and organelle arrangements that support their specific tasks. In particular, T cells rapidly change their shape and cellular function through the establishment of cell surface and intracellular polarity in response to a variety of cues. This review focuses on the contribution of the microtubule-based dynein/dynactin motor complex, the tubulin and actin cytoskeletons, and different organelles to the formation of the antigen-driven immune synapse.
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martn-cfreces2018frontierssailing
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| Authors | ;Noa Beatriz Martín-Cófreces;Noa Beatriz Martín-Cófreces;Francisco Sánchez-Madrid;Francisco Sánchez-Madrid |
| Journal | sudebno-meditsinskaia ekspertiza |
| Year | 2018 |
| DOI | 10.3389/fimmu.2018.01174 |
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