autonomic dysregulation, cognitive impairment, and symptoms of psychosis as an unusual presentation in an anti-aquaporin 4-positive patient

Clicks: 146
ID: 227540
2017
We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation, cognitive impairment, and symptoms of psychosis. Only a few previous cases have been described with similar psychiatric symptoms. Brain MRI showed an abnormal hyperintense T2 signal of the hypothalamus and, to a lesser extent, a minor hyperintense signal of the right optic nerve. Her symptoms and MR abnormalities improved after high-dose methylprednisolone.
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Authors ;Annabel M. Ruiter;Jan F. Meilof;Rosemarijn R.J. Somanje-Bolweg;Erik van Gorsel;Nynke F. Kalkers
Journal journal of neuro-oncology
Year 2017
DOI 10.1159/000455942
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