Wnt/β-catenin signalling in prostate cancer - Nature Reviews Urology

Clicks: 199
ID: 267984
2012
Dysregulation of Wnt signalling, a hallmark of which is the stabilization of the transcriptional co-activator β catenin, can lead to several types of cancer, including prostate cancer. Activation of the Wnt/β catenin pathway has effects on prostate cell proliferation, differentiation and the epithelial–mesenchymal transition. In this Review, the authors discuss how the pathway is activated and consider the possible therapeutic application of drugs that target Wnt/β catenin signalling.
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kypta2012naturewnt/β-catenin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Robert M. Kypta;Jonathan Waxman;Robert M. Kypta;Jonathan Waxman;
Journal Nature Reviews Urology
Year 2012
DOI doi:10.1038/nrurol.2012.116
URL
http://dx.doi.org/10.1038/nrurol.2012.116##access-options
Keywords
gene expression mutation prostate cancer cell signalling

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