Single-molecule sequencing of an individual human genome

Clicks: 217
ID: 268757
2009
Recent advances in high-throughput DNA sequencing technologies have enabled order-of-magnitude improvements in both cost and throughput. Here we report the use of single-molecule methods to sequence an individual human genome. We aligned billions of 24- to 70-bp reads (32 bp average) to approximatel …
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Authors Pushkarev D;Neff NF;Quake SR;;
Journal Nature Biotechnology
Year 2009
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