Determination of the pH of the Cryptococcus neoformans vacuole
Clicks: 181
ID: 269169
2002
We have previously demonstrated the antifungal activity of the weak bases chloroquine and quinacrine against Cryptococcus neoformans. Quinacrine, being fluorescent, was seen to be concentrated within a complex vacuolar structure within the cryptococcal cell. Here we determined the pH of this compart …
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ts2002medicaldetermination
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| Authors | Harrison TS;Chen J;Simons E;Levitz SM;; |
| Journal | medical mycology |
| Year | 2002 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
microscopy
fluorescence
hydrogen-ion concentration
fluoresceins
pmid:12146766
doi:10.1080/mmy.40.3.329.332
t s harrison
j chen
s m levitz
cryptococcus neoformans / chemistry*
cryptococcus neoformans / ultrastructure
confocal
vacuoles / chemistry*
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