De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
Clicks: 129
ID: 269386
2011
Induced pluripotent stem cells (iPSCs) are generated from somatic cells by the transduction of defined transcription factors, and this process involves dynamic changes in DNA methylation. While the reprogramming of somatic cells is accompanied by demethylation ...
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jaenisch2011genesde
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| Authors | Mathias Pawlak, Rudolf Jaenisch;Mathias Pawlak;Rudolf Jaenisch; |
| Journal | genes & development |
| Year | 2011 |
| DOI | 10.1101/gad.2039011 |
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