Adrenergic Downregulation in Critical Care: Molecular Mechanisms and Therapeutic Evidence

Clicks: 116
ID: 269690
2020
Catecholamines remain the mainstay of therapy for acute cardiovascular dysfunction. However, adrenergic receptors quickly undergo desensitization and downregulation after prolonged stimulation. Moreover, prolonged exposure to high circulating catecholamines levels is associated with several adverse …
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Authors Belletti A;Landoni G;Lomivorotov VV;Oriani A;Ajello S;;
Journal journal of cardiothoracic and vascular anesthesia
Year 2020
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