RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function
Clicks: 209
ID: 270179
2006
The Cre/loxP recombinase system for performing conditional gene targeting experiments has been very useful in exploring genetic pathways that control both the development and function of pancreatic beta-cells. One particular line of transgenic mice (B6.Cg-Tg(Ins2-cre)25Mgn/J), commonly called RIP-Cr …
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| Authors | Lee JY;Ristow M;Lin X;White MF;Magnuson MA;Hennighausen L;; |
| Journal | The Journal of biological chemistry |
| Year | 2006 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
male
Rats
Promoter Regions
transgenic
gene targeting
insulin-secreting cells / pathology
insulin-secreting cells / physiology*
pmid:16326700
doi:10.1074/jbc.m512373200
ji-yeon lee
michael ristow
lothar hennighausen
glucose intolerance / genetics
insulin / genetics*
integrases / genetics*
|
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