The nature and character of the transition state for the ADP-ribosyltransferase reaction

Clicks: 235
ID: 272592
2008
Exotoxin A (ExoA) from Pseudomonas aeruginosa is an important virulence factor that belongs to a class of exotoxins that are secreted by pathogenic bacteria which cause human diseases such as cholera, diphtheria, pneumonia and whooping cough. We present the first crystal structures, to our knowledge …
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r2008embothe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jørgensen R;Wang Y;Visschedyk D;Merrill AR;;
Journal EMBO reports
Year 2008
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/18583986
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Molecular humans pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't mutation protein binding bacterial toxins / metabolism protein structure structure-activity relationship mutagenesis secondary bacterial toxins / genetics exotoxins / genetics x-ray site-directed pseudomonas aeruginosa / metabolism* virulence factors / genetics crystallography adp ribose transferases / chemistry bacterial toxins / chemistry exotoxins / chemistry exotoxins / metabolism virulence factors / chemistry virulence factors / metabolism pmid:18583986 pmc2515215 doi:10.1038/embor.2008.90 rené jørgensen yolanda wang a rod merrill adp ribose transferases / genetics adp ribose transferases / metabolism* nad / chemistry nad / metabolism* peptide elongation factor 2 / chemistry peptide elongation factor 2 / genetics peptide elongation factor 2 / metabolism* pseudomonas aeruginosa / growth & development

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