Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development

Clicks: 174
ID: 272641
1997
In situ hybridization of mouse embryo sections demonstrated expression of mRNAs encoding two polypeptide inhibitors (p18INK4c and p19INK4d) of cyclin D-dependent kinase (CDK) 4 and CDK6 in the central nervous system. No expression of two other INK4 members, p16INK4a and p15INK4b, was observed. The p …
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Authors Zindy F;Soares H;Herzog KH;Morgan J;Sherr CJ;Roussel MF;;
Journal Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
Year 1997
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9372237
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't P.H.S. brain / drug effects cyclin-dependent kinase inhibitor p16 / metabolism carrier proteins / biosynthesis cyclin-dependent kinases / antagonists & inhibitors* kainic acid / pharmacology F Zindy M F Roussel cyclin-dependent kinase 4 proto-oncogene proteins* excitatory amino acid agonists / pharmacology tumor suppressor proteins* pmid:9372237 h soares brain / embryology* cell cycle proteins* cyclin-dependent kinase inhibitor p16 / biosynthesis* cyclin-dependent kinase inhibitor p18 cyclin-dependent kinase inhibitor p19 dentate gyrus / embryology enzyme inhibitors / metabolism* neocortex / embryology

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