Both copy number and sequence variations affect expression of human DEFB4
Clicks: 205
ID: 274526
2010
Copy number variations (CNVs) were found to contribute massively to the variability of genomes. One of the best studied CNV region is the beta-defensin cluster (DEFB) on 8p23.1. Individual DEFFB copy numbers (CNs) between 2 and 12 were found, whereas low CNs predispose for Crohn's disease. A further …
| Reference Key |
m2010genesboth
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Groth M;Wiegand C;Szafranski K;Huse K;Kramer M;Rosenstiel P;Schreiber S;Norgauer J;Platzer M;; |
| Journal | genes and immunity |
| Year | 2010 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Comparative Study
Cells
Cultured
Base Sequence
Molecular Sequence Data
Gene Expression Regulation*
Promoter Regions
genetic variation / genetics
genetic / genetics
haplotypes / genetics
pmid:20445567
doi:10.1038/gene.2010.19
m groth
c wiegand
m platzer
dna copy number variations / genetics*
beta-defensins / biosynthesis*
beta-defensins / genetics*
|
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.