Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1

Clicks: 259
ID: 274643
1996
The cyclin D-dependent kinases CDK4 and CDK6 trigger phosphorylation of the retinoblastoma protein (RB) late in G1 phase, helping to cancel its growth-suppressive function and thereby facilitating S-phase entry. Although specific inhibition of cyclin D-dependent kinase activity in vivo can prevent c …
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Authors Hirai H;Sherr CJ;;
Journal molecular and cellular biology
Year 1996
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8887674
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Molecular animals humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't amino acid sequence Comparative Study P.H.S. cell line 3T3 Cells Transcription Factors / metabolism* Base Sequence sequence homology amino acid kinetics cloning recombinant proteins / biosynthesis transcription factors / biosynthesis transfection phosphorylation dna / metabolism binding sites consensus sequence recombinant proteins / metabolism transcription factors / chemistry spodoptera protein-serine-threonine kinases / metabolism c j sherr cyclin-dependent kinase 4 proto-oncogene proteins / chemistry cyclin d retinoblastoma protein / metabolism saccharomyces cerevisiae pmid:8887674 pmc231647 doi:10.1128/mcb.16.11.6457 h hirai cyclin-dependent kinase 6 cyclin-dependent kinases / metabolism cyclins / metabolism* proto-oncogene proteins c-myb recombinant proteins / chemistry trans-activators / chemistry

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