Cancer - An Insurgency of Clones.

Clicks: 220
ID: 49893
2017
Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.
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Authors Gisselsson, David;Egnell, Robert;
Journal Trends in cancer
Year 2017
DOI S2405-8033(16)30188-1
URL
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