Eosinophilic esophagitis: early diagnosis is the key

Amanda B Muir,1 Terri Brown-Whitehorn,2 Bridget Godwin,1 Antonella Cianferoni11Gastroenterology Division, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; 2Allergy Division, The Children’s Hospital of Philadelphia, Philadelphia, PA, USACorrespondence: Antonella CianferoniGastroenterology Division, The Children’s Hospital of Philadelphia, ARC1216G, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USATel +1 267 294 1952Email Cianferonia@email.chop.eduAbstract: Eosinophilic esophagitis (EoE) is a disorder which affects all ages, from infancy through adulthood. It typically affects atopic individuals (Table 1) and is a chronic allergic disorder, with foods ubiquitous in the diet being the most described trigger of this isolated eosinophilic inflammation of the esophagus in both adults and children. This inflammatory process leads to esophageal symptoms such as dysphagia and feeding intolerance. In this review, we provide a brief overview of the current state of EoE therapy and symptomatology and then try to make the case for early diagnosis and treatment to prevent some of the long-term consequences of esophageal inflammation.Keywords: eosinophilic esophagitis, early, diagnosis, stenosis, pain