[Application of polygenic risk scores in risk prediction and precision prevention of complex diseases: opportunities and challenges].
Clicks: 189
ID: 66654
2019
Along with the rapid progress in the field of human genomics, genome-wide association studies have successfully identified numerous risk loci for complex diseases. Polygenic risk scores can predict disease risk by integrating the effects of multiple susceptibility loci, and begin to show good performance for improving risk prediction, screening strategy and precision prevention. This paper briefly reviews the recent progress of polygenic risk scores in disease prevention, and summarizes the opportunities and challenges of its application.
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hang2019applicationzhonghua
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| Authors | Hang, D;Shen, H B; |
| Journal | zhonghua liu xing bing xue za zhi = zhonghua liuxingbingxue zazhi |
| Year | 2019 |
| DOI | 10.3760/cma.j.issn.0254-6450.2019.09.001 |
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