A novel Salvialactomine from the callus culture of Salvia santolinifolia Boiss.
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ID: 67561
2018
A novel compound Salvialactomine (1) along with two other unusual occurring natural products Pentatriacontanoic acid 1, 3-dihydroxypropyl ester (2) and 5-Methylflavone (3) were isolated from the callus of Salvia santolinifolia Boiss. Callus was initiated on MS medium containing NAA (0.5 mg/L) and further sub-cultured on MS medium supplemented with NAA with BA (0.5 + 1.5 mg/L). The structures of isolated compounds were determined by using mass spectrometry, 1D, and 2D-NMR techniques. Compounds 1, and 3 were tested for two different cancer cell lines, i.e. Hela (Cervical cancer cell) and PC-3 (Prostate cancer cells). IC was found as > 30 using Doxorobicin (0.912 ± 0.12 μmol L) as a standard.
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| Authors | Jan, Tour;Qadri, Raiha;Naqvi, Beena;Adhikari, Achyut;Nadeem, Said;Muhammad, Akhtar; |
| Journal | Natural product research |
| Year | 2018 |
| DOI | 10.1080/14786419.2017.1311887 |
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