Aristolactam-Type Alkaloids from Orophea enterocarpa and Their Cytotoxicities

Clicks: 262
ID: 90199
2012
A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively.
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nuntasaen2012aristolactamtypeinternational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nuntasaen, Narong;Pompimon, Wilart;Tuntiwechapikul, Wirote;Meepowpan, Puttinan;Thaichana, Pak;Buayairaksa, Mongkol;Nayyatip, Sanchai;
Journal International journal of molecular sciences
Year 2012
DOI DOI not found
URL
http://www.mdpi.com/1422-0067/13/4/5010/
Keywords
chemistry Organic Chemistry Biology (General) Science (General) Science Diseases of the circulatory (Cardiovascular) system dermatology diseases of the genitourinary system. urology

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